Endothelial progenitor cells: Implications for cardiovascular disease

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Endothelial progenitor cells in cardiovascular disorders.

The important role of the vascular endothelium in cardiovascular health is increasingly recognized. However, mature endothelial cells possess limited regenerative capacity. There is therefore much interest in circulating endothelial progenitor cells (EPCs) among the scientific community, especially into their purported role in maintenance of endothelial integrity and function, as well as postna...

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Endothelial progenitor cells in cardiovascular diseases.

Endothelial dysfunction has been associated with the development of atherosclerosis and cardiovascular diseases. Adult endothelial progenitor cells (EPCs) are derived from hematopoietic stem cells and are capable of forming new blood vessels through a process of vasculogenesis. There are studies which report correlations between circulating EPCs and cardiovascular risk factors. There are also s...

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Endothelial progenitor cells in coronary artery disease.

In the last two decades a great deal of evidence has been collected on the key role of endothelial progenitor cells (EPC) in the mechanisms of vascular healing. The role of EPC as a marker of vascular health and prognosis of cardiovascular disease is already consolidated. This review aims to examine and evaluate recent data regarding EPC, as biomarkers, prognostic factor and potential therapy i...

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ژورنال

عنوان ژورنال: Cytometry Part A

سال: 2009

ISSN: 1552-4922,1552-4930

DOI: 10.1002/cyto.a.20669